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retatrutide phase 2 trial obesity nejm 2023 triple agonist hormone receptor for metabolic dysfunction-associated steatotic liver disease: a randomized ...
Among participants who did have type 2 diabetes, the article says the same trials consistently showed lower HbA1c along with reduced mortality and cardiovascular events
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“Primary objectives for pharmaceutical weight loss should focus on optimizing diet composition and nutrient intake in addition to managing side effects.” Here, the study emphasized adhering to general guidance on higher protein intake calculated for g/kg for lean mass preservation—presenting meal replacement shakes as a relatively low-calorie, low-fat source of protein that can be supplemented with vitamins and minerals to help fill dietary gaps
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